WebDec 12, 2024 · PSTPIP2 administration suppressed kidney injury in response to cisplatin treatment, suggesting that PSTPIP2 can be a part of a useful therapeutic strategy for … WebJan 3, 2024 · Cisplatin-induced acute kidney injury (CI-AKI) is a significant co-morbidity of chemotherapeutic regimens. While this condition is associated with substantially lower survival and increased economic burden, there is no pharmacological agent to …
Cisplatin-induced renal injury is independently mediated by
WebSep 1, 2024 · These results suggest that ABs, through iPGE 2-dependent mechanisms, might have a relevant role in the natural history of cisplatin-induced acute kidney failure … WebDec 21, 2024 · Myo-inositol, a carbocyclic sugar, is believed to be relevant to renal pathobiology since the kidney is the major site for its catabolism. Its role in acute kidney … dickinson side by side shotguns for sale
Myo-Inositol Supplementation Alleviates Cisplatin-Induced Acute Kidney …
WebCisplatin is a potent antineoplastic agent derived from platinum and commonly used in the treatment of head and neck, bladder, ovarian, and testicular malignanc Cisplatin-Induced Acute Kidney Injury and Renal Salt Wasting Syndrome Federal Practitioner WebMay 1, 2015 · Cisplatin causes direct necrosis and apoptosis of proximal tubule cells but also induces a series of inflammatory changes that mediate kidney injury. In vitro cisplatin induced enhanced expression of TLRs … WebApr 1, 2024 · However, cisplatin medication has many side effects, such as ototoxicity, neurotoxicity, nephrotoxicity, nausea, and vomiting [ 35, 97, 98, 99 ]. Nephrotoxicity occurs because cisplatin is taken up by the proximal tubular cells and can concentrate up to five times more than the cisplatin in the serum [ 35, 97 ]. dickinsons innovative style