WebDec 1, 2016 · For example, FoxO3a activates FasL transcription, the ligand for the Fas-dependent cell death pathway or pro-apoptotic Bim gene and initiates apoptosis. FoxO3a also induces the expression of cell cycle progression inhibitors including p27 and CyclinD1, thus stalling the G1/S phase transition . Here, we investigated whether the survival … Web销售进口SIGMA试剂、abcam抗体、R&D抗体、CST抗体、ATCC细胞、BD公司、GE公司产品。 公司客户遍布大学、研究所、医院、卫生、商品检验检疫、制药公司、生物技术公司和食品工业等单位。
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WebOct 15, 2024 · Previously, FoxO3a has been found to modulate autophagy through inducing expression of several autophagy-related genes, including LC3, Beclin-1, and P62 [5, 33]. Inhibition of FoxO3a exhibited effects of neuroprotection following TBI and induction of TBI was found to translocate cytosolic FoxO3a into nucleus [ 33 ]. WebForkhead box O (FOXO) proteins are a family of transcription factors with four members in mammals, namely FOXO1, FOXO3a, FOXO4, and FOXO6. FOXO factors, originally … ready not baseball spring training week
Elucidating the role of the FoxO3a transcription factor in the …
WebMonoclonal Antibody for studying FoxO3a. Cited in 187 publications. Validated for WB, IP, IHC, IF, F. Highly specific and rigorously validated in-house, FoxO3a (D19A7) Rabbit Monoclonal Antibody (CST #12829) is … WebApr 19, 2024 · The primary antibodies used in this study were AKT (1:1000; total and Ser473, Cell Signaling Technology Inc., Danvers, MA, USA), TOR (1:2000; total and Ser2448, CST), S6K1 (1:2000; total and Thr421/Ser424, CST), FOXO3a (1:3000; total and Ser253, Abcam, Cambridge, MA, USA), MAFBX and MURF-1 (1:4000; Zen … WebFeb 14, 2024 · The transcription factor FoxO3A is a key determinant of cancer cell homeostasis, playing a dual role in survival/death response to metabolic stress and cancer therapeutics. We recently described a novel mitochondrial arm of the AMPK-FoxO3A axis in normal cells upon nutrient shortage. how to take care of delphinium